Therapeutic Category Hub

Cognitive & Neuro Health

Neuropeptides investigated for regulating BDNF expression, neurotransmitter balance, and neurovascular plasticity under cognitive demand.

Peptides in this Category (3)

Target compounds

Clinical TrialsTuftsin Analog

Selank

A synthetic heptapeptide derived from human tuftsin, researched for anxiolytic, nootropic, and immunomodulatory properties without sedation.

Biological Half-Life~15 - 20 minutes (rapid neural uptake)

Clinical TrialsACTH (4-10) Heptapeptide Analog

Semax

A synthetic neuroactive heptapeptide combining an ACTH fragment with a Pro-Gly-Pro tripeptide, researched for nootropic actions, BDNF stimulation, and ischemic stroke recovery.

Biological Half-Life~15 - 20 minutes (rapid neural uptake and multi-hour genomic downstream activation)

Research CompoundDelta Sleep-Inducing Peptide

DSIP

A naturally occurring nonapeptide isolated from cerebral venous blood during induced slow-wave sleep, researched for circadian regulation and autonomic stress buffering.

Biological Half-Life~15 - 30 minutes

Related Clinical Studies (1)

Browse All Studies →

Preclinical2014-04-15

Semax Modulates Expression of Neurotrophins (BDNF, NGF) and Their Receptors in Ischemic Rat Brain

Mechanistic molecular study illustrating how Semax confers neuroprotection during cerebral ischemia by robustly upregulating Brain-Derived Neurotrophic Factor (BDNF) and TrkB signaling.

Molecular Genetics and GenomicsRead Study