A synthetic heptapeptide derived from human tuftsin, researched for anxiolytic, nootropic, and immunomodulatory properties without sedation.
~15 - 20 minutes (rapid neural uptake)
GABA-A Receptors
C33H57N11O9
Administered via intranasal spray for direct olfactory-to-brain uptake.
Small or observational human data; warrants clinical caution.
Animal (rodent) and in-vitro cellular assays. Does NOT prove human efficacy.
Formal regulatory oversight and verified clinical development phase.
Evidence classification for Selank: Human clinical data is strictly differentiated from non-human animal and in-vitro laboratory assays.
C33H57N11O9
Thr-Lys-Pro-Arg-Pro-Gly-Pro
Developed by the Institute of Molecular Genetics of the Russian Academy of Sciences, Selank combines the immunogenic tuftsin fragment with a Pro-Gly-Pro tripeptide to enhance metabolic stability. Research highlights anxiolytic activity comparable to benzodiazepines but without addictive potential, sedation, or cognitive impairment.
Modulates GABAergic neurotransmission, influences monoamine neurotransmitter metabolism (serotonin and dopamine turnover), and upregulates brain-derived neurotrophic factor (BDNF) mRNA in the hippocampus.
Peer-reviewed publications, clinical trials, and preclinical research investigating Selank.
Documented literature dosing intervals and published clinical trial protocols.
Biological delivery routes and standardized laboratory reconstitution principles.
Administered via intranasal spray for direct olfactory-to-brain uptake.
Lyophilized peptides must be reconstituted using sterile bacteriostatic water (0.9% benzyl alcohol) and maintained strictly refrigerated between 2°C - 8°C (36°F - 46°F), shielded from light.
View Full Preparation ProtocolCompiled from peer-reviewed biomedical literature, public clinical trial registries, and recognized reference catalog databases.
Pharmacological profiles, receptor targets, and clinical data are verified against primary registries:
Community research topics, peptide nomenclature, and aliases are cross-referenced with public catalogs:
This topic was identified through research of publicly available peptide resources and peer-reviewed literature. Peptide Health Digest provides independent scientific explanations and does not endorse commercial distribution.
